Phytochemistry & Biodiscovery

Traditional medicinal systems all over the world have applied herbal drugs over millennia. Research based on this enormous resource creates new insights into the traditional medical systems and the elucidation of the active principles of such plants provides new bio-active compounds which can be developed for future application  in therapy.

e.g.:

Sheridan H, Kopp B, Krenn L, Gu, D, Sendker J. Traditional Chinese herbal medicine preparation: Invoking the Butterfly Effect. Science, vol 350, no. 6262 Suppl, pp. S64-S66, 2015. TCM_butterly.pdf

Mair CE, Liu R, Atanasov AG, Wimmer L, Nemetz-Fiedler D, Sider N, Heiss EH, Mihovilovic MD, Dirsch VM, Rollinger JM. Piperine Congeners as Inhibitors of Vascular Smooth Muscle Cell Proliferation. Planta Medica: natural products and medicinal plant research, vol 81, no. 12-13, pp. 1065-1074, 2015. 10.1055/s-0035-1546165

Wu H, Waldbauer K, Tang L, Xie L, McKinnon R, Zehl M, Yang H, Xu H, Kopp B. Influence of Vinegar and Wine Processing on the Alkaloid Content and Composition of the Traditional Chinese Medicine Corydalis Rhizoma (Yanhusuo). Molecules: a journal of synthetic organic and natural product chemistry, vol 19, no. 8, pp. 11487-11504, 2014. 10.3390/molecules190811487